Analysis Note

ControlHuman normal brain tissue

Application

This Anti-PINK1 Antibody, clone N4/49 is validated for use in IH, WB for the detection of PINK1.

Western Blot Analysis: A previous lot of MABN18 recognized PINK1 in HEK cells and a rat brain LSP, as reported by an independent laboratory (UC Davis/NIH NeuroMab Facility; www.neuromab.org/[email protected]).

General description

Mutations in the PTEN-induced kinase 1 (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with recessive early-onset Parkinson disease. Data suggests that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Quality

Evaluated by Immunohistochemistry in human normal brain tissue.

Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected PINK1 in human normal brain tissue.

Specificity

This antibody recognizes PINK1.

Target description

63 kDa Observed